Complete blood count alterations in disseminated histoplasmosis

Complete blood count alterations in disseminated histoplasmosis

Classical histoplasmosis is a cosmopolitan fungal infection caused by Histoplasma capsulatum variety capsulatum.1 H. capsulatum is a dimorphic fungus found in nature in its filamentous form, consisting of branched hyphae, which produce tuberculate macroconidia, the infective form of the fungus. When cultivated at 37 ◦C and in the tissues of infected people, it presents as budding yeast cells.1 ...

Disseminated histoplasmosis in peripheral blood smear.

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The complete blood count.

Disseminated histoplasmosis diagnosed in a peripheral blood smear.

FIGURE 1 Peripheral blood smear multiple yeasts in neutrophil (arrow). 1,000x magnification – Giemsa staining). A 40-year-old man with human immunodeficiency virus (HIV) infection, diagnosed in 2008, and irregular use of antiretroviral therapy, was admitted to the emergency room with diarrhea, asthenia, fever, and weight loss of 4kg in the previous 10 days. His evacuations were watery, with no ...

Subdural Empyema in Disseminated Histoplasmosis

A 34-year-old man presented with two episodes of generalized tonic–clonic seizures and fever for 1 day. Two months back, he was admitted with high grade fever, productive cough, cervical lymphadenopathy, left lower lobe consolidation, and multiple skin abscesses. The pus from the abscess was drained and the abscess wall histopathology revealed intracellular oval shaped fungal organisms with nar...